What is your favorite eye color: blue, green or, maybe, hazel? Perhaps your favorite eye color is the original color of brown. More than a few thousand years ago, everyone had the same eye color, brown. But through a DNA shuffle by nature, the melanin of the iris (which creates the color of the eye) had a “switch” installed that caused the brown to dilute to blue. The gene where the switch was created is called, oculocutaneous albinism II, or OCA2 for short. This gene controls a protein called P protein. The actual use of this P protein is unknown. But, what we do know is that it affects the melanin which causes skin, hair and eye color. People with this mutation often have blonde hair, creamy white skin, light-colored eyes and problems with vision.